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Adenylosuccinic acid

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Catalog No. T14129Cas No. 19046-78-7
Alias Aspartyl adenylate, Adenylosuccinate

Adenylosuccinic acid (Adenylosuccinate) is a purine nucleotide cycle metabolite and a novel inducer of the Nrf2 cell protector. It can be used for research on Duchenne muscular dystrophy (DMD).

Adenylosuccinic acid

Adenylosuccinic acid

😃Good
Catalog No. T14129Alias Aspartyl adenylate, AdenylosuccinateCas No. 19046-78-7
Adenylosuccinic acid (Adenylosuccinate) is a purine nucleotide cycle metabolite and a novel inducer of the Nrf2 cell protector. It can be used for research on Duchenne muscular dystrophy (DMD).
Pack SizePriceAvailabilityQuantity
5 mg188 €35 days
10 mg299 €35 days
25 mg610 €35 days
50 mg1.121 €35 days
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Product Introduction

Bioactivity
Description
Adenylosuccinic acid (Adenylosuccinate) is a purine nucleotide cycle metabolite and a novel inducer of the Nrf2 cell protector. It can be used for research on Duchenne muscular dystrophy (DMD).
In vivo
Adenylosuccinic acid (oral administration; 3-3000 µg/mL; 6 weeks) significantly alleviated the pathologic features of DMD (Duchenne muscular dystrophy) in mice. Its effects were demonstrated by a reduction in the proportion of central nuclear fibers in the mdx tibialis anterior muscle, a reduction in lipid accumulation, an inhibition of connective tissue infiltration, and a reduction in Ca2+ content. [1]
AliasAspartyl adenylate, Adenylosuccinate
Chemical Properties
Molecular Weight463.29
FormulaC14H18N5O11P
Cas No.19046-78-7
SmilesO[C@H]1[C@H](N2C=3C(N=C2)=C(N[C@@H](CC(O)=O)C(O)=O)N=CN3)O[C@H](COP(=O)(O)O)[C@H]1O
Relative Density.2.19g/cm3
Storage & Solubility Information
Storagestore at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

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TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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